I purchased a Bamboo tablet and pen several years ago to use with Flash and Fireworks (and hopefully soon Photoshop).
I used to only use the pen when I was trying to do graphics, but I have found over the past few months, that the pen makes a much better mouse!
It is so much more accurate than that clunky mouse! I can point to exactly what I want, and the pen has both a right and left button
on it (just like a Windows mouse).
There are some great free programs for writing out problems in math and sending them to my students. When I use a Windows machine, I use the Windows Journal, but now that I am mostly on a Mac, I use Jarnal
Using the pen instead of a mouse made for a very easy transition to my Mobi (from eInstruction)!
I highly recommend getting and using it for everything on your computer.